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Practice Test 4: Nelson Physics 11 Answers for the 2016 United States .

Nelson

Grade

Physics 11u

Subject

Nelson

Part

Nelson

Chapter

Mathematics

1

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2

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Biology

1

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2

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Chemistry

1

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English

1

Nelson

2

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Physics

1

Nelson

2

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Sociology

1

Nelson

2

Nelson

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The chemokine CXCL16 has been shown to induce angiogenesis and to promote breast cancer cell migration and invasion. High CXCL16 expression levels have been associated with metastasis in other types of cancer. Moreover, we have previously shown that CXCL16 protein level was higher in tumor tissue of patients with distant relapse than in the distant metastasis-free group, suggesting that CXCL16 might also serve as a risk factor for metastasis \[[@B16],[@B17]\].

As CXCL16 has been shown to be involved in many processes associated with breast cancer progression, we wanted to characterize its potential impact on the metastatic process. We therefore compared CXCL16 gene expression of breast tumor tissue from patients with and without distant relapse. This approach has been used successfully in our previous study to evaluate the gene expression profiles of tumor tissue of patients with and without distant relapse \[[@B16]\]. The aim of the current study was to replicate the finding of the previous study. As we found CXCL16 expression in all of the breast tumors analyzed, this study did not validate the previous observation that CXCL16 expression is increased in metastatic tumors. However, in agreement with the previous study, the current finding showed that C
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